专利名称：Compositions and methods for treatment of
prostate and other cancers
发明人：Martin E. Gleave,Palma Rocchi,Maxim
Signaevsky,Eliana Beraldi
申请号：US10605498申请日：20031002公开号：US07101991B2公开日：20060905
摘要：Therapeutic agents which target heat shock protein (hsp) 27 in vivo are used toprovide treatment to individuals, particularly human individuals, suffering from prostatecancer and other cancers that overexpress hsp27. A therapeutic agent, for example anantisense oligonucleotide or RNAi nucleotide inhibitor with sequence specificity for hsp27mRNA, for example human hsp27 mRNA, is administered to an individual suffering fromprostate cancer or some other cancer expressing elevated levels of hsp 27 in atherapeutically effective amount. The therapeutic agent is suitably formulated into apharmaceutical composition which includes a pharmaceutically acceptable carrier, andpackaged in dosage unit form. A preferred dosage unit form is an injectable dosage unitform.
申请人：Martin E. Gleave,Palma Rocchi,Maxim Signaevsky,Eliana Beraldi
地址：Vancouver CA,Vancouver CA,Vancouver CA,Vancouver CA
国籍：CA,CA,CA,CA
代理机构：Marina Larson & Associates, LLC
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