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Methods and materials for the preparation of metal

来源:好走旅游网
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专利名称:Methods and materials for the preparation

of metal labelled antibody solutions

发明人:David K. Johnson,Patrick E. Rogers申请号:US07/118148申请日:19871106公开号:US05130118A公开日:19920714

摘要:The present invention provides a metal ion scavenging procedure and antibodycompositions for radioimmunoscintigraphy and cytotoxic radioimmunotherapy havingchelator concentrations of greater than about 10.sup.-4 M which are optimized withrespect to their metal binding capacity such that highly efficient labelling of the antibodyis achieved in a simple one step procedure using readily available sources of radiometalions.

申请人:ABBOTT LABORATORIES

代理人:Wean Khing Wong,Lawrence S. Pope,Daniel R. Curry

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