专利名称:Methods and materials for the preparation
of metal labelled antibody solutions
发明人:David K. Johnson,Patrick E. Rogers申请号:US07/118148申请日:19871106公开号:US05130118A公开日:19920714
摘要:The present invention provides a metal ion scavenging procedure and antibodycompositions for radioimmunoscintigraphy and cytotoxic radioimmunotherapy havingchelator concentrations of greater than about 10.sup.-4 M which are optimized withrespect to their metal binding capacity such that highly efficient labelling of the antibodyis achieved in a simple one step procedure using readily available sources of radiometalions.
申请人:ABBOTT LABORATORIES
代理人:Wean Khing Wong,Lawrence S. Pope,Daniel R. Curry
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