专利名称：New use of glutaminyl cyclase inhibitors发明人：Cynis, Holger,Demuth, Hans-Ulrich,Hoffmann, Torsten,Schilling, Stephan
申请号：AU2008220785申请日：20080228公开号：AU2008220785B2公开日：20130221
摘要：The present invention relates in general to an inhibitor of a glutaminyl peptidecyclotransferase, and use thereof for the treatment and/or prevention of a disease ordisorder selected from the group consisting of inflammatory diseases selected from a.neurodegenerative diseases, e.g. mild cognitive impairment (MCI), Alzheimer's disease,neurodegeneration in Down Syndrome, Familial British Dementia, Familial Danish
Dementia, multiple sclerosis, b. chronic and acute inflammations, e.g. rheumatoid arthritis,atherosclerosis, restenosis, pancreatitis, c. fibrosis, e.g. lung fibrosis, liver fibrosis, renalfibrosis, d. cancer, e.g. cancer/hemangioendothelioma proliferation, gastric carcinomas, e.metabolic diseases, e.g. hypertension, f. and other inflammatory diseases, e.g.
neuropathic pain, graft rejection/graft failure/graft vasculopathy, HIV infections/AIDS,gestosis, tuberous sclerosis. Further, the invention relates to a respective diagnosticmethod, assay and kit.
申请人：Probiodrug AG
代理人：Watermark Patent and Trade Marks Attorneys
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