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Rationally designed antibodies

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专利名称:Rationally designed antibodies发明人:Bowdish, Katherine S.,Frederickson,

Shana,Renshaw, Mark

申请号:EP04077554.6申请日:20011205公开号:EP1589034B1公开日:20081119

摘要:Antibodies or fragments thereof having CDR regions replaced or fused withbiologically active peptides are described. Flanking sequences may optionally beattached at one or both the carboxy-terminal and amino-terminal ends of the peptide incovalent association with adjacent framework regions. Compositions containing suchantibodies or fragments thereof are useful in therapeutic and diagnostic modalities.

申请人:ALEXION PHARMA INC

地址:US

国籍:US

代理机构:Dempster, Robert Charles

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