专利名称：Automatic registration of images发明人：Gisli Hreinn Halldorsson,Einar
Stefansson,Jon Atli Benediktsson,RobertArnar Karlsson,Sveinn Hakon
Hardarson,Thor Eysteinsson,James M. Beach
申请号：US11146278申请日：20050607
公开号：US20060276698A1公开日：20061207
专利附图：
摘要：The present invention relates to a system for automatically evaluating oxygen
saturation of the optic nerve and retina, said system comprising: image capturing systemfurther comprising: a fundus camera (), a four wavelengths beam splitter (), a digital imagecapturing device (), a computer system, image processing software performing in real-time the steps of: registering set of multi-spectral images () by, binarizing the multi-spectral image (), find the all the border regions of each image by finding the regionincluding the straight line that passes the most number of points in the region (), use theorientation of the borders to evaluate the orientation of each spectral image (), equalizethe orientation of each spectral image by rotating the spectral image (), edge detect eachspectral image (), estimate the translation between the spectral images based on theedges of adjacent images (), transform the images to a stack of registered images (),locating blood vessels () in each of the multi-spectral images by, retrieving registeredspectral images (), for each spectral image, remove defective pixels (), enhance imagecontrast (), perform top-hat transform using structuring element larger than the largestvessel diameter (), binarize each image (), apply filter for smoothing the image (), combineall the spectral images using binary AND operator (), skeletonize the resulting image (),prune the skeleton image (), re-grow the pruned image (), locate junction points (),evaluating the width of the blood vessels () by calculating the normal vector to the vesseldirection to, estimate the direction and position of the vessel profile, evaluate positionsof vessel walls based on the vessel profile obtained, evaluate vessel width based on theposition of the vessel walls, selecting samples for calculating optical density, calculatingthe optical density ratio (), evaluating oxygen saturation level (), and presenting theresults (), wherein presenting the results may include presenting numerical and visualrepresentation of the oxygen saturation.
申请人：Gisli Hreinn Halldorsson,Einar Stefansson,Jon Atli Benediktsson,Robert ArnarKarlsson,Sveinn Hakon Hardarson,Thor Eysteinsson,James M. Beach
地址：Reykjavik IS,Reykjavik IS,Reykjavik IS,Reykjavik IS,Reykjavik IS,Reykjavik IS,SlidellLA US
国籍：IS,IS,IS,IS,IS,IS,US
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